Cathinone C86 identified as eutylone

The substance found and alerted by KnowYourStuffNZ in testing earlier this month, previously known only as C86, has now been identified as eutylone.

Eutylone, also known as bk-EBDB or n-ethylbutylone, is a stimulant in the cathinone family (sometimes called “bath salts”). It was first synthesised in the 1960s and first reported to  European Early Warning Systems in 2014. Reports of recreational use began to appear about 2 years ago.

KnowYourStuffNZ detected the first sample of this substance in December 2018. We have detected five samples of eutylone this year, in locations from upper North Island to lower South Island. All were obtained as MDMA, and were described as a white powder that tends to clump together – however it may also be around in other formats. Anecdotal reports from NZers who have used this substance thinking it was MDMA suggest it may be responsible for several hospitalisations.

In the absence of a spectrometer, reagents can be used to test for the presence of eutylone. Testing with the Marquis reagent will give a yellow/orange colour, and the Mandelin reagent turns a muddy greenish-brown. Meanwhile if a substance contains MDMA, both Marquis and Mandelin reagents will turn black. It is important to note that other cathinones have been found mixed with MDMA, so a positive test result for MDMA does not mean a substance is unadulterated.

Eutylone is not well researched and very little information about it is available. The following information has been put together from a combination of user reports, safety data sheets, and references in scientific journals.

Dosage:

Oral doses of between 35mg and 150mg have been reported, however the average dose is reported as 60-100mg. 150mg was described as ‘very intense’.

Duration

4-6 hours

Effects

The effects are described as subtle, calming, social, serotonergic (loved up), euphoric, and not particularly stimulating.

Sensations of physical warmth and tingling were described in several reports. One user reported feeling unusual heart activity.

Dangers/negatives

Users reported redose compulsion, with most redosing every 1-2 hours.  Because this is a stimulant, repeated redosing can lead to restlessness and insomnia, and eventually psychosis if the user does not sleep.

Safety Data Sheet information suggests it may be irritating to mucous membranes.

Users have reported raised heartbeats, and as it constricts blood vessels this substance can also raise blood pressure and cause numb or cold extremities.

Eutylone has been identified as present in one death in the US, however the victim had also taken fentanyl and thus the role of eutylone in the death is not clear.

Harm reduction information

Avoid snorting this substance.

Avoid taking with other stimulants (eg cocaine or MDMA), dissociatives (eg ketamine, DXM, or GHB/GBL), or alcohol.

If you intend to take eutylone, be aware that it is a very new substance with little confirmed information available, and therefore approach with extreme caution. Take only a fraction of the expected dose and wait at least an hour before taking more.

Always make sure a trusted person knows what you are doing.

If you experience dizziness, nausea, racing heart, or numbness in the extremities, seek medical help and be honest about what you have taken.

Dunedin cathinone capsule

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ALERT: White powder in clear capsules containing unknown cathinone C86

FURTHER UPDATE 1 May: We’ve now identified this as eutylone, a new cathinone. You can find harm reduction advice in our more detailed eutylone post.

UPDATE Saturday 19.00: After more analysis we believe this is not n-ethylpentylone as previously stated. It appears to be an unknown cathinone that we’re calling “C86”. The harm reduction advice remains the same – treat with caution. This substance is so new that we do not know of the health risks.

Original alert: N-ethylpentylone found in powder obtained as MDMA

KnowYourStuffNZ tested pills in Dunedin today and found a particularly dangerous substance called n-ethylpentylone an unknown cathinone that we’re calling “C86”.
Two samples of white powder in clear capsules from different sources were tested and each contained a mixture of n-ethylpentylone and ethylone this single substance. We have seen this substance previously at a summer event in the North Island.

N-ethylpentylone C86 is a stimulant from the cathinone family, also called “bath salts”. It may produce short-lived euphoria followed by a long period of overstimulation including racing heart, high blood pressure, anxiety, overheating, and inability to sleep for up to 36 hours. Cathinones have been associated with deaths overseas and hospitalisations in New Zealand. Because of the high redose compulsion and low active dose, it is very easy to overdose. You can read more about n-ethylpentylone at our website. We called it “this summer’s crap drug“. We don’t know what C86 is exactly, other than that it’s a cathinone and fairly similar in chemical structure to n-ethylpentylone.

The identified pills are medium sized clear capsules containing a chalky white powder that clumps together.

When tested with Marquis reagent the samples turned orange and with Mandelin they turned dark orange. These colour changes indicate a cathinone.

Testing with the more reliable FT-IR spectroscopy suggests these pills contain a mixture of of n-ethylpentylone and ethylone an unknown cathinone which we are calling C86 that is similar to n-ethylpentylone. The amount of n-ethylpentylone C86 present may vary between pills. Alternatively, this may be a new and unknown cathinone. Yup, it’s a new one alright.

It is possible that These pills have spread throughout New Zealand, being seen by KnowYourStuffNZ from one of the country to the other, therefore any substance that looks similar to this should be treated as dangerous regardless of your location.

N-ethylpentylone has been detected in powders and pills of various colours. In total, approximately 15% of “MDMA” tested over New Years was found to contain n-ethylpentylone.

Please approach all untested substances with extreme caution. C86 has not, to our knowledge, been seen before and there is no information about safety, dosage, risks, and interactions with other drugs. We recommend avoiding this.
– safest of all, do not take it
– if consuming, start small, start slow – take a third or less, and wait at least an hour before having more
– do not snort or inject
– do not mix with other substances, including alcohol
– do not take alone


If you think you may have inadvertently consumed n-ethylpentylone a cathinone and are concerned, please contact your nearest medical service and be honest about what you believe you have taken.

KnowYourStuffNZ is a not-for-profit social enterprise funded entirely by donations from the community. If you value our work, please donate.

Nosebleeds are the least of your worries – why snorting is a bad idea

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Remember when you were four and your Mum used to tell you not to put things up your nose?  Turns out lots of kiwis didn’t listen. According to Adam Winstock of the Global Drug Survey, 30% of kiwis who use MDMA insufflate (snort) it. That’s nearly twice the global average.

There’s a general view out there that snorting MDMA gives you more ‘bang for buck’ because when snorted the high comes on faster and more intensely.  However it also wears off faster, leading to higher likelihood of redosing – so over the course of an evening a user may end up taking more than usual, which is both expensive and risky. Snorting also carries its own set of risks:

  • Putting dry, potentially irritant powders on the nasal lining can lead to injury, loss of sense of smell, and long term respiratory problems.
  • When you snort a substance much of it goes directly to the bloodstream, bypassing the stomach and liver filters. This is what leads to the faster, more intense high.  However this lack of filtering can also exacerbate the negative effects of the drug, such as anxiety and nausea.
  • Faster routes of administration are associated with higher risk of forming dependence.
  • What if it’s not the drug you think it is?

This last one is a real concern in New Zealand. By now it’s old news that cathinone substitution is an issue here. We’ve talked about it at length this summer. We’ve found cathinones in samples presumed to be MDMA and in ones obtained as cocaine, both substances commonly snorted by kiwis.

Remember how we said above that a faster, more intense high can also exacerbate the negative effects? If the ‘MDMA’ is actually n-ethylpentylone and you snort 100mg of it, you’ve just bypassed the stomach and liver filters on a triple dose and you’re most likely in for a faster, more intense, up to 36-hour-long very unpleasant time that may well land you in hospital or worse. 


We hear this story far too often – someone snorts what they think is MDMA and then comes to us with a list of scary symptoms ending with “That definitely wasn’t MDMA.” The bottom line is that these people are lucky to be alive. While they have probably learned their lesson, there are still many people out there who snort powders without knowing how risky it is.

To lower your chances of death, remember the following:

  • Listen to your Mum – don’t put random stuff up your nose
  • Don’t let your friends put random stuff up their noses either
  • Unless it’s been tested, it’s *all* random stuff.

Stay safe out there NZ.

KnowYourStuffNZ is a not-for-profit social enterprise funded entirely by donations from the community. If you value our work, please donate.

Deliberately Deceptive Drug Mixtures Found This Summer

Testing by KnowYourStuffNZ this summer has revealed that some festival goers have been sold deliberately deceptive mixtures of drugs. Some mixtures were sold as MDMA but contained only small amounts of MDMA alongside more toxic chemicals. Some mixtures were sold as cocaine but instead contained mixes of stimulants and anaesthetics.

Our testing has shown that the quality of substances sold on the illicit market is variable and poor. In many cases, substances sold are not as expected. However, this summer we have seen mixtures that appear to be made up to deliberately mislead people.

For example, cocaine produces a numbing effect in the nose and mouth. We have seen mixtures that contain no cocaine at all but only benzocaine and cathinones (“bath salts”). The benzocaine (a local anaesthetic found in cough lozenges) produces the numbing effect; the cathinones duplicate the stimulant effects. In these cases, the cathinones were n-ethylbuphedrone and ethylmethcathinone, which have longer duration and more toxic effects than cocaine.

Several samples supposedly of MDMA were a mix of MDMA and cathinones. We believe that these mixtures were made up to fool reagent testing – the MDMA produces dark colours with commonly-available reagent tests, masking the colours from the unwanted cathinones. These combinations are particularly risky due to the different potencies of these substances. One sample seen was 50/50 mix of MDMA and n-ethylpentylone (a new substance that we called “this summer’s crap drug”). An active dose of MDMA is around 100 mg; a dose of n-ethylpentylone is 30 mg. If someone weighs out 100 mg of this mixture, they will take nearly two doses of n-ethylpentylone (already a risky dose) and only half a dose of MDMA..

Inevitably, unregulated markets have poor quality control and unscrupulous dealers will sell products that maximise their profits, putting consumers’ health at risk. Pill testing allows drug users to discover the quality of their purchases and avoid these risks.  We recommend that all drug users test before they ingest any substance.

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KnowYourStuffNZ uses both reagent testing and infra-red spectrometry to discover these mixtures. However, an infra-red spectrometer costs $50,000 and this is not accessible outside of events that KnowYourStuffNZ attends.

Reagents for testing are available for much more affordable prices from suppliers such as Hempstore, but as the mixtures found this summer demonstrate, reagents have their limits. They would have identified the substitute cocaine; they would not have detected the adulterated MDMA. We still recommend reagent testing to drug users despite the limitations, as some testing is better than none – however the results from reagent testing are no guarantee and all substances should be approached with caution.

KnowYourStuffNZ is a not-for-profit social enterprise funded entirely by donations from the community. If you value our work, please donate.

“Faulty batch” warning not helpful

A warning has been released by Canterbury DHB after 9 people presented at Christchurch hospital Saturday night.

Unfortunately it appears that the DHB is speculating about what the people had taken in the absence of knowing for certain, and have released a vague warning about a ‘faulty batch’. There is no such thing as a faulty batch.

KnowYourStuffNZ in its testing of ‘MDMA’ this year has found:

Any of these would have associated potential dangers, but none of them are a ‘faulty batch of MDMA’.

The information in the alert is of almost no use to users. The warning contains no mention that the substance could be something completely different, no description of the substance, and no information about what sort of symptoms a user may experience that would signify danger. This warning might as well say “Don’t take MDMA.” Such an approach has been entirely ineffective at stopping people taking MDMA to date.

This is why New Zealand needs a properly-functioning Early Warning System, with protocols for what an effective, harm-reduction-focused warning looks like. At the very least, a warning should contain:

  • a description of the substance so users know what to avoid
  • information about the content of the substance – if this is not known, that should be made clear and warnings should refrain from speculation
  • information about symptoms that signal danger.

We have released four alerts about substances of concern since the beginning of 2018. Right now, we are NZ’s Early Warning System. This is not good enough. The NZ government has been talking for years about implementing one, but the talk has not resulted in action. Warnings are left to DHBs with limited knowledge of illicit drugs and harm reduction, and community groups such as ourselves.

The government needs to step up and progress the national Early Warning System immediately. Meanwhile, we will continue to release information about substances of concern as they arise.

On the topic of the Christchurch mystery drug, our advice is:

  • Approach all unknown substances with extreme caution.
  • Unless they have been tested and confirmed to contain the desired substance and only the desired substance, they are *all* unknown.
  • Substitution, adulteration, and extremely high dose pills are all currently being found in the market.
  • When using, it is much better to take a fraction of a dose and await developments (at least an hour) than to take the whole thing without knowing what it is and risk a trip to the hospital.

Be careful out there, folks.

[EDIT: Three weeks after thirteen people were hospitalised in Christchurch after ingesting this mystery substance, NZ Police confirmed that the substance was n-ethylpentylone. We published our warning about this substance two weeks before this event and five weeks before the Police. This shows that KnowYourStuffNZ is already acting as New Zealand’s drug early warning system. However, we are constrained by the legal grey area that we operate in. Clarifying the law and allowing us to operate openly will save lives.]

KnowYourStuffNZ is a not-for-profit social enterprise funded entirely by donations from the community. If you value our work, please donate.